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$595,000
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Property Description
Some homes check the boxes. Others make you feel something the moment you arrive. Originally built in 1956 as two neighboring fish camps, this one-of-a-kind waterfront home has been thoughtfully transformed into a warm, inviting retreat while preserving the character that makes it so special. Sitting on 0.7 acres with more than 100 feet of shoreline on Big Lake Santa Fe, this is the kind of property where mornings begin with breathtaking sunrises over the water and evenings end on the porch after a day on the lake. With nearly 500 acres of surface water and depths reaching up to 26 feet, Big Lake Santa Fe is one of North Central Florida's most treasured lakes, offering year-round boating, skiing, fishing, paddleboarding, and endless days on the water. The property even includes its own natural lagoon with a small boat ramp, and the dock was extensively improved in 2023 with new pilings where needed, an extended platform, and a 5,000-pound Dolphin boat lift ready for your ski boat or pontoon. Inside, every room reflects the care and creativity of the current owners. The remodeled kitchen features custom cabinetry, updated countertops, appliances, and fixtures, while beautiful luxury vinyl plank flooring flows throughout the living spaces and new tile enhances both bathrooms. Thoughtful details-from the wood accents and designer lighting to the carefully chosen finishes-create a home that feels both timeless and effortlessly welcoming. One of the highlights is the incredible 31-foot screened porch, added in 2020. It's the perfect place to sip your morning coffee as the sun rises over the lake, watch afternoon storms roll across the water, or gather with friends long after the sun goes down. The home offers 2 bedrooms, 2 baths, plus a versatile bonus room that could easily serve as a third bedroom, office, bunk room, or creative studio. A unique guest bath connects directly to the utility room and exterior door, making cleanup after swimming, fishing, or working outdoors incredibly convenient. Outside, the property continues to impress. Mature cypress trees frame the lake without stealing the view, while a fully fenced yard with an electric gate offers privacy and peace of mind. A powered workshop and separate storage shed provide plenty of space for tools, hobbies, lake toys, and equipment. Nearly every major component has been improved, including a metal roof, updated windows and doors, remodeled kitchen and bathrooms, luxury flooring, exterior paint, new water heater (2026), gutters with guards, finished laundry room, sump pump (2021), septic service, and much more-allowing the next owner to simply move in and start enjoying lake life. Whether you're searching for a full-time residence, a weekend escape, or a vacation rental with exceptional appeal, this property offers something that's becoming increasingly difficult to find: authentic character, modern updates, and a front-row seat to one of North Central Florida's most beautiful lakes. Some houses are just places to live. This one is where memories are made. Need more room for family or guests? The beautifully built 2021 custom home directly across the street is also available. Purchase both together at a discounted package price to create your own private Big Lake Santa Fe retreat. (GC541232)
Full Property Details
Full Property Details for 7521 NE 222nd St
General
- Price: $595,000
- Taxes: $4,840 (2025)
- Status: Active
- Type: Single Family
- Source: MidFloridaRegionalMLS
- MLS ID: GC541231
- Updated: 6/27/2026
- Added to Site: 14 day(s) ago
Rental Information
- Min. Lease: No Minimum
Interior
- Number of Rooms: 3
- Interior Features: Ceiling Fan(s), Eating Space In Kitchen, High Ceilings, Primary Bedroom Main Floor, Split Bedroom, Vaulted Ceiling(s), Walk-In Closet(s)
- Appliances: Dishwasher, Dryer, Range, Range Hood, Refrigerator, Washer
- Furnishings: Unfurnished
- Flooring: Ceramic Tile, Luxury Vinyl
Rooms
Bathrooms
- Total Bathrooms: 2
- Full Bathrooms: 2
Bedrooms
- Total Bedrooms: 2
Other Rooms
- Laundry: Inside
Exterior
- Exterior Features: Private Yard, Rain Gutters, Sliding Doors, Storage
- Deck/Patio: Rear Porch, Screened
- Porch/Patio/Deck: Rear Porch, Screened
Location
- Area: 32666 - Melrose
- County: Alachua
- Development Name: 32666 - Melrose
- Subdivision: N/A
- Driving Directions: From the intersection of SR 26 and SR 21, go West on SR 26. Take a Right (North) onto NW 221st. Take a Right (East) onto NE 69th Ln. Turn Left (North) onto NE 222nd St, home will be on the right
- Direction Faces: West
School Information
- Elementary School: Chester Shell Elementary School-AL
- Middle School: Hawthorne Middle/High School-AL
- High School: Hawthorne Middle/High School-AL
Community
- Community Name: 32666 - Melrose
Heating & Cooling
- Cooling Type: Central Air
- Heating Type: Central
Utilities
- Sewer: Septic Tank
- Water District: LAKE SANTE FE
- Water: Well
- Utility Description: Electricity Connected
Structural Information
- Exterior Const.: Concrete
- Roof: Metal
- Stories/Levels: One
- Square Feet: 1,042
- Sq. Ft. Source: Public Records
- Year Built: 1956
Additional Structures
- Other Structures: Shed(s), Workshop
Lot Features
- Property View: Water
- Lot Size (Acres): 0.7
- Lot Size (Sq. Ft.): 30,492
- Lot Size: 30492
- Street/Road Desc.: Dirt
- Fencing (Description): Chain Link
Water Features
- Water Front: Yes
- Water View: Yes
- Water Access: Yes
- Water Access Desc: Lake
- Water Extras: Yes
- Water Front Name: LAKE SANTE FE
- Water Front Desc.: Lake Front
Financial Considerations
- Tax Amount: $4,840.1
- Tax Year: 2025
Disclosures and Reports
- Ownership: Fee Simple
- Special Conditions: None
- Legal Description: SANTA FE SHORES PB D-20 COM 348.4 FT W & 1881.02 FT N OF NW COR OF NE1/4 OF NE1/4 SEC 15 N 1 DEG W 205 S 82 DEG E 132.23 FT N 2 DEG E 162 FT N 88 DEG W 13.4 FT POB N 88 DEG W 128.1 FT N 1 DEG W 100 FT S 88 DEG E 348.1 FT WATERS EDGE S/LY 100 FT N 88 DEG W 210 FT POB OR 4631/1781
- Flood Zone Info: X
- APN: 18673005000
- Property ID: 18673005000
Listed by Keller Williams Gainesville Realty Partners
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Schools
Schools serving 7521 NE 222nd St
School District:Alachua County School District
| Name | Grades | Distance |
|---|---|---|
Chester Shell Elementary School 21633 Southeast 65 Avenue, Hawthorne, FL 32640 | K-5 | 9.1 mi |
Hawthorne Middle/High School 21403 Southeast 69th Avenue, Hawthorne, FL 32640 | 6-12 | 9.3 mi |
Disclaimer:
School attendance boundaries provided by ATTOM Data Solutions and are for reference only. Contact the school directly to verify enrollment eligibility.
Price & Sales History for 7521 NE 222nd St
Date
Details
Price
Change
Source
6/27/2026
Listed
$595,000
122.01%
MLS
9/21/2018
Sold
$268,000
—
Public Record
Disclaimer: Historical sales information is derived from public records provided by the county offices. Information is not guaranteed and should be independently verified.
Tax History
Tax History for 7521 NE 222nd St
Year
Property Taxes
Change
Tax Assessment
Change
2025
$4,840
3%
$269,670
3%
2024
$4,711
3%
$262,070
3%
2023
$4,592
11%
$254,436
11%
2021
$4,130
-7%
$228,846
-7%
2022
$4,441
8%
$247,025
9%
2021
$4,130
1%
$226,909
2%
2019
$4,096
16%
$221,807
11%
2018
$3,534
-3%
$199,400
—
2017
$3,653
-3%
$200,100
1%
2016
$3,749
-24%
$197,600
-4%
2015
$4,934
—
$205,200
—
2014
$4,926
—
$205,400
—
2013
$4,911
—
$206,100
—
Disclaimer: Historical tax information is derived from public records provided by the county offices. Information is not guaranteed and should be independently verified.
Estimate the Cost
Estimate the Cost for 7521 NE 222nd St
7521 NE 222nd Street, Melrose, FL 32666 (MLS# GC541231) is a Single Family property with 2 bedrooms and 2 full bathrooms. 7521 NE 222nd Street is currently listed for $595,000 and was received on June 27, 2026. Want to learn more about 7521 NE 222nd Street? Do you have questions about finding other Single Family real estate for sale in Melrose? You can browse all Melrose real estate or contact a Coldwell Banker agent to request more information.
