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$749,000 -$50,000 (-6.26%) Price Reduced

  • For Sale
  • Active
  • Retail
  • 7,400 Sq. Ft.
  • Updated 16 hours ago
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Discover a rare downtown La Crosse opportunity at 422-424 Main St. Formerly ''The Main'' event venue, this property blends historic character with modern versatility--featuring a large stage, lighting, bar, kitchen equipment, and a corner office suite. The expansive lower level offers ideal storage or additional build-out potential. The upper level at 424 Main is a luxury apartment currently used as a short-term rental, providing proven income. Keep the event use or reimagine the space for your vision--steps from restaurants, nightlife, and the riverfront. A flexible commercial property in the heart of downtown energy. All equipment is negotiable for a seamless transition. We'll help you shape the vision.

Full Property Details for 422 Main St #424

General

  • Price: $749,000
  • Taxes: $12,914 (2024)
  • Status: Active
  • Type: Retail
  • Source: MetroMLS_Milwaukee_Wirex
  • MLS ID: 1944606
  • Updated: 2/10/2026
  • Added to Site: 67 day(s) ago

Additional Information

  • Other Features: Display Window, Fixtures, Living Space Available, Office(s), Restrooms, Roof Sign

Location

  • Municipality: City
  • County: La Crosse
  • Driving Directions: Take Hwy 53 (3rd or 4th Streets) to downtown La Crosse, turn on Main St property between 4th and 5th St.
  • Dist. to Freeway: Less than 1 Mile, 1 to 3 Miles
  • Location Details: Business District

Heating & Cooling

  • Heating/Cooling: Central Air Conditioning, Natural Gas

Utilities

  • Water/Sewer: Municipal Sewer, Municipal Water

Structural Information

  • Structure Type: Office(s), Other, Retail, Special Purpose
  • Exterior Const.: Brick
  • Basement Desc.: Full
  • Roof: Rubber
  • Ceiling Height: 11 to 15 Feet, 8 to 10 Feet
  • Drive-In Clearance: No Truck Door
  • Stories Description: 2
  • Square Feet: 7,400
  • Year Built: 1900

Lot Features

  • Lot Size (Acres): 0.14
  • Frontage: High Visibility, Near Public Transit, Town/City Road
  • Zoning: Commercial

Financial Considerations

  • For Sale/Rent/Lease: For Sale Only
  • Tax Amount: $12,914.41
  • Tax Year: 2024

Listed by United Country Midwest Lifestyle Properties LLC

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Listing agent

— 422 Main St #424 —

  • United Country Midwest Lifestyle Properties LLC

josh@midwestlifestyleproperties.com

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NMLS#: 1598647

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Save up to an additional 20% by bundling your home and auto together!

Be ready to buy your new home!

with our affiliated lender
NMLS#: 1598647

Get Pre-Approved

Find the right home insurance for your new home!

with our affiliated in-house agency

Request a Quote

Save up to an additional 20% by bundling your home and auto together!

Schools serving 422 Main St #424

School District:La Crosse School District
NameGradesDistance
Emerson Elementary School, La Crosse, WI
2101 Campbell Road, La Crosse, WI 54601
PK-51.3 mi
Logan High School
1500 Ranger Drive, La Crosse, WI 54603
9-122.4 mi
Disclaimer: School attendance boundaries provided by Pitney Bowes and are for reference only. Contact the school directly to verify enrollment eligibility.

Price & Sales History for 422 Main St #424 Get Price Alerts and Save Property

Date
Details
Price
Change
Source
2/10/2026
Price Reduced
$749,000
-6.26%
MLS
12/05/2025
Listed
$799,000
45.27%
MLS
7/23/2020
Sold
$550,000
—
Public Record
Get Price Alerts and Save Property
Disclaimer: Historical sales information is derived from public records provided by the county offices. Information is not guaranteed and should be independently verified.

Tax History for 422 Main St #424

Year
Property Taxes
Change
Tax Assessment
Change
2024
$11,764
2%
$561,200
—
2023
$11,586
5%
$561,200
—
2022
$10,988
-22%
$561,200
4%
2021
$14,029
300%
$538,200
293%
2020
$3,503
2%
$136,800
—
2019
$3,431
-7%
$136,800
6%
2018
$3,684
—
$129,000
—
2017
$3,679
—
$129,000
—
2016
$3,674
—
$129,000
—
2015
$3,677
—
$129,000
—
2014
$3,665
-3%
$129,000
—
2013
$3,776
—
$129,000
—
View All
Disclaimer: Historical tax information is derived from public records provided by the county offices. Information is not guaranteed and should be independently verified.

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Listed by United Country Midwest Lifestyle Properties LLC

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422 Main St #424, La Crosse, WI 54601 (MLS# 1944606) is a Retail property. 422 Main St #424 is currently listed for $749,000 and was received on December 05, 2025. Want to learn more about 422 Main St #424? Do you have questions about finding other Retail real estate for sale in La Crosse? You can browse all La Crosse real estate or contact a Coldwell Banker agent to request more information.

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